methyl 5-((tert-butyldimethylsilyl)oxy)-2-methylbenzoate
methyl 5-((tert-butyldimethylsilyl)oxy)-2-methylbenzoate
CAS: 866028-37-7
Molecular Formula: C15H24O3Si
methyl 5-((tert-butyldimethylsilyl)oxy)-2-methylbenzoate - Names and Identifiers
methyl 5-((tert-butyldimethylsilyl)oxy)-2-methylbenzoate - Physico-chemical Properties
| Molecular Formula | C15H24O3Si |
| Molar Mass | 280.43 |
| Density | 0.980±0.06 g/cm3(Predicted) |
| Boling Point | 319.4±30.0 °C(Predicted) |
methyl 5-((tert-butyldimethylsilyl)oxy)-2-methylbenzoate - Introduction
methyl 5-((tert-butyldimethylsilyl)oxy)-2-methylbenzoate is an organic compound with the chemical formula C15H26O3Si. The following is an introduction to some of its properties, uses, methods and safety information:
Nature:
-Appearance: colorless liquid
-Melting point:-24 ° C
-Boiling point: 160-161 ° C
-Density: 0.959g/cm3
-Refractive Index: 1.4517
Use:
methyl 5-((tert-butyldimethylsilyl)oxy)-2-methylbenzoate is commonly used as an intermediate in organic synthesis. It can be used to synthesize drugs, pesticides and other organic compounds.
Method:
The preparation of methyl 5-((tert-butyldimethylsilyl)oxy)-2-methylbenzoate is usually carried out by the following steps:
1.2-methyl benzoic acid methyl ester reacts with t-butyl lithium to generate the corresponding lithium salt.
2. React lithium salt with t-butyl chlorosilane to generate methyl 5-((tert-butyldimethylsilyl)oxy)-2-methylbenzoate.
Safety Information:
- methyl 5-((tert-butyldimethylsilyl)oxy)-2-methylbenzoate exposure may cause irritation and may cause damage to the eyes, skin and respiratory system.
-During operation, good ventilation should be maintained and protective gloves, masks and goggles should be worn if necessary.
-When handling or storing the compound, observe the relevant safety practices and follow proper waste disposal procedures.
Please note that the use and handling of chemicals involves certain risks, and it is recommended to operate under the guidance of professionals.
Nature:
-Appearance: colorless liquid
-Melting point:-24 ° C
-Boiling point: 160-161 ° C
-Density: 0.959g/cm3
-Refractive Index: 1.4517
Use:
methyl 5-((tert-butyldimethylsilyl)oxy)-2-methylbenzoate is commonly used as an intermediate in organic synthesis. It can be used to synthesize drugs, pesticides and other organic compounds.
Method:
The preparation of methyl 5-((tert-butyldimethylsilyl)oxy)-2-methylbenzoate is usually carried out by the following steps:
1.2-methyl benzoic acid methyl ester reacts with t-butyl lithium to generate the corresponding lithium salt.
2. React lithium salt with t-butyl chlorosilane to generate methyl 5-((tert-butyldimethylsilyl)oxy)-2-methylbenzoate.
Safety Information:
- methyl 5-((tert-butyldimethylsilyl)oxy)-2-methylbenzoate exposure may cause irritation and may cause damage to the eyes, skin and respiratory system.
-During operation, good ventilation should be maintained and protective gloves, masks and goggles should be worn if necessary.
-When handling or storing the compound, observe the relevant safety practices and follow proper waste disposal procedures.
Please note that the use and handling of chemicals involves certain risks, and it is recommended to operate under the guidance of professionals.
Last Update：2024-04-09 15:18:04
